1  Contract research

Ø    in regenerative biology with in vitro models to measure bioavailability, permeability, cell regeneration, cell proliferation and/or wound healing (e.g. for cosmetics)

Ø    measurement of possible adverse toxic effects of ingested and/or inhaled materials or beneficial effects using our newly developed and proprietary digestive tract model (e.g. food, nutraceuticals in different formulations; nanoparticular matter)

Ø    cell-free screening of antioxidant and cell-based screening of anti-inflammatory substances by using our exclusive test for inhibition or induction of oxidative stress upon formation of superoxide radicals (TIIOS) or after H2O2-induced oxidative stress

2   Screening of pharmacological compounds/targets for evaluation of the therapeutic window

3   Determination of bioavailability, acute, subchronic &        chronic toxicity and allergenic potential of pure substances        and complex mixtures and matrices

4      Cytotoxicity screening of substances used in various consumer products such as textiles, leather, glue, dyes and varnishes, plastics, furniture, wood, toys, building materials and many others

5   Biocompatibility testing of medical devices according to EN ISO 10993-5

6   Mutagenicity screening using Ames MPF 98/100 from        Xenometrix GmbH, Switzerland